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Title

Antibiotic Resistance Genes Online (ARGO): A Database on vancomycin and b-lactam resistance genes

 

Authors

Joy Scaria1, Umamaheswaran Chandramouli2, Sanjay Kumar Verma1*

 

Affiliation

1Center for Biotechnology, Biological Sciences Group, Birla Institute of Technology & Science, Pilani-333031, India, 2Teledata Informatics Limited, Chennai, India.

 

E-mail*

skverma@bits-pilani.ac.in; * Corresponding author

 

Article Type

 

Web database

 

Date

 

received  February 14, 2005; revised March 14, 2005; accepted  March 15, 2005; published online March 17, 2005

 

Abstract

 

Vancomycin and β-lactams are antibiotics that inhibit gram positive bacteria by interfering with cell wall synthesis. However, continuous use of antibiotics results in the emergence of multi-drug resistant (MDR) bacterial strains. Here, we describe ARGO, a database containing gene sequences conferring resistance to these two classes of antibiotics. It is designed as a resource to enhance research on the prevalence and spread of antibiotic resistance genes. ARGO is the first attempt to compile the resistance gene sequence data with state specific information.

 

Availability

http://www.argodb.org/

 

Keywords

 

antibiotic resistance; β-lactamase; vancomycin; gene; sequence

 

Citation

 

J. Scaria, C. Umamaheswarn & S. K. Verma, Bioinformation 1(1): 5-7, (2005)

 

Edited by

 

P. Kangueane

 

ISSN

 

0973-2063

 

Publisher

 

Biomedical Informatics

 

Copyright

 

Publisher

 

Copyright Transfer Agreement

 

The authors of published articles in Bioinformation automatically transfer the copyright to the publisher upon formal acceptance. However, the authors reserve right to use the information contained in the article for non commercial purposes.

 

License

 

This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited.