Title

Antibiotic Resistance Genes Online (ARGO): A Database on vancomycin and b-lactam resistance genes

Authors

Joy Scaria¹, Umamaheswaran Chandramouli², Sanjay Kumar Verma^1*

Affiliation

¹Center for Biotechnology, Biological Sciences Group, Birla Institute of Technology & Science, Pilani-333031, India, ²Teledata Informatics Limited, Chennai, India.

E-mail*

skverma@bits-pilani.ac.in; * Corresponding author

Article Type

Web database

Date

received  February 14, 2005; revised March 14, 2005; accepted  March 15, 2005; published online March 17, 2005

Vancomycin and β-lactams are antibiotics that inhibit gram positive bacteria by interfering with cell wall synthesis. However, continuous use of antibiotics results in the emergence of multi-drug resistant (MDR) bacterial strains. Here, we describe ARGO, a database containing gene sequences conferring resistance to these two classes of antibiotics. It is designed as a resource to enhance research on the prevalence and spread of antibiotic resistance genes. ARGO is the first attempt to compile the resistance gene sequence data with state specific information.

Availability

http://www.argodb.org/

Keywords

antibiotic resistance; β-lactamase; vancomycin; gene; sequence

Citation

J. Scaria, C. Umamaheswarn & S. K. Verma, Bioinformation 1(1): 5-7, (2005)

Edited by

P. Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.