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Beyond Bioinformatics |
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Title |
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Salivary biomarkers in psychobiological medicine
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Authors |
Francesco Chiappelli1,*, Francisco Javier Iribarren2, Paolo Prolo1
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Affiliation |
1 CHS 63-090, UCLA School of Dentistry, Los Angeles, CA 90095-1668, USA; 2 UCLA School of Medicine, Los Angeles, CA 90095-1668, USA
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Phone |
+310-794-6625
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Fax |
+310-7947109; * Corresponding author
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Article Type |
Current Trends
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Date |
received December 21, 2006; revised December 28, 2006; accepted December 29, 2006; published online December 29, 2006
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Abstract |
The value of salivary biomarkers for diagnostic and prognostic assessments has become increasingly well established in medicine, pharmacology, and dentistry. Certain salivary components mirror the neuro-endocrine status of the organism. Other saliva products are protein in nature, and can serve to reflect immune surveillance processes. The autonomic nervous system regulates the process of salivation, and the concentration of yet other salivary components, such as α-amylase, which provide a reliable outcome measure of the sympathetic response. Here, we discuss molecular technologies that have permitted giant steps in the utilization of salivary samples and micro-fluidics for the benefit of diagnostic medicine and dentistry, and their putative role in springing forward research in psychobiology.
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Keywords
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saliva; biomarker; physiology; psychobiology; diagnosis |
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Citation |
Chiappelli et al., Bioinformation 1(8): 331-334 (2006)
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Edited by |
P. Kangueane
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ISSN |
0973-2063
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Publisher |
Biomedical Informatics Publishing Group
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Copyright |
Publisher
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Copyright Transfer Agreement |
The authors of published articles in Bioinformation automatically transfer the copyright to the publisher upon formal acceptance. However, the authors reserve right to use the information contained in the article for non commercial purposes.
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License |
This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited.
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