Title

CALCOM: A software for calculating the center of mass of proteins

Authors

Susan Costantini^{1, 2}, Antonella Paladino^{1, 2}, and Angelo M. Facchiano^{1, 2, *}

Affiliation

¹Laboratory of Bioinformatics and Computational Biology, Institute of Food Science, CNR, via Roma 52 A/C, 83100 Avellino, Italy; ²CRISCEB, Research Center of Computational and Biotechnological Sciences, Second University of Naples, via Costantinopoli 16, 80138 Naples, Italy

Email

angelo.facchiano@isa.cnr.it

39 0825 299625

39 0825 299813; * Corresponding author

Article Type

Web Server

Date

received January 08, 2008; revised January 18, 2008; accepted January 26, 2008; published February 09, 2008

Abstract

The center of mass of a protein is an artificial point useful for detecting important and simple features of proteins structure, shape and association.

CALCOM is a software which calculates the center of mass of a protein, starting from PDB protein structure files. In the case of protein complexes and of protein-small ligand complexes, the position of protein residues or of ligand atoms respect to each protein subunit can be evaluated, as well as the distance among the center of mass of the protein subunits, in order to compare different conformations and evaluate the relative motion of subunits.

The service is available at the URL: http://bioinformatica.isa.cnr.it/CALCOM/

Keywords

center of mass; proteins; protein subunits distance; web-software

Citation

Costantini et al., Bioinformation 2(7): 271-272 (2008)

Edited by

I. Roterman

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.