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Title

 

 

 

 

 

SNUFER: A software for localization and presentation of single nucleotide polymorphisms using a Clustal multiple sequence alignment output file

 

Authors

 

Marco A. B. Mansur1, Giovana P. Cardozo1, Elaine V. Santos1 and Mozart Marins1, 2, *

 

Affiliation

 

 

1Unidade de Biotecnologia, UNAERP, Ribeirão Preto, SP, Brazil; 2Heranza - Biotecnogia, Ribeirão Preto, SP, Brazil.

 

Email

 

marins@heranza.com.br; * Corresponding author

 

Article Type

 

Software

 

Date

 

received August 13, 2008; accepted September 17, 2008; published October 17, 2008

Abstract

SNUFER is a software for the automatic localization and generation of tables used for the presentation of single nucleotide polymorphisms (SNPs). After input of a fasta file containing the sequences to be analyzed, a multiple sequence alignment is generated using ClustalW ran inside SNUFER. The ClustalW output file is then used to generate a table which displays the SNPs detected in the aligned sequences and their degree of similarity. This table can be exported to Microsoft Word, Microsoft Excel or as a single text file, permitting further editing for publication. The software was written using Delphi 7 for programming and FireBird 2.0 for sequence database management. It is freely available for noncommercial use and can be downloaded from http://www.heranza.com.br/bioinformatica2.htm.

 

Keywords

 

software; single nucleotide polymorphisms; multiple sequence alignment; ClustalW

 

Citation

 

Mansur et al., Bioinformation 3(2): 63-64 (2008)

 

Edited by

 

P. Kangueane

 

ISSN

 

0973-2063

 

Publisher

 

Biomedical Informatics

 

License

 

 

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.