Title

Convergence pattern studies of folate receptor

Authors

 Kalidoss Ramamoorthy¹ and Rama Shanker Verma^1, *

Affiliation

¹Stem cell and Molecular biology Laboratory, Department of Biotechnology, Indian Institute of Technology Madras, Chennai 600 036 TN India

Email

 vermars@iitm.ac.in; * Corresponding author

Article Type

Hypothesis

Date

received April 29, 2008; revised October 15, 2008; accepted October 30, 2008; published December 06, 2008

Abstract

Gene patterns and sequences of folic acid synthesizing genes that are converged as meaningful patterns during evolution in the higher eukaryotes has been identified using sequence alignment and pattern analysis.  Based on the finding, we are postulating that part of genes that are involved in synthesis of folic acid in lower eukaryotes, are converged into meaningful similar functional domains of folate receptor in higher eukaryotes. 

Keywords

 PROSITE patterns; MUSCLE algorithm; Folate receptors (FRs); convergence

Citation

 Ramamoorthy & Verma, Bioinformation 3(4): 168-172 (2008)

Edited by

P. Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.