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Title
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Specific gene hypomethylation and cancer: New insights into coding region feature trends
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Authors
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Elias Daura-Oller, Maria Cabre, Miguel A. Montero, Jose L. Paternain, Antoni Romeu
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Affiliation
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Biochemistry and Biotechnology Department, Faculty of Chemistry, Rovira i Virgili, University (URV), c/ Marcel·li Domingo, s/n. Campus Sescelades, 43007 Tarragona, Spain
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Phone |
34977558188
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Fax |
34977558232
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Article Type
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Hypothesis
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Date
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received December 02, 2008; accepted January 12, 2009; published April 21, 2009
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Abstract
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Giving coding region structural features a role in the hypomethylation of specific genes, the occurrence of G+C content, CpG islands, repeat and retrotransposable elements in demethylated genes related to cancer has been evaluated. A comparative analysis among different cancer types has also been performed. In this work, the inter-cancer coding region features comparative analysis carried out, show insights into what structural trends/patterns are present in the studied cancers.
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Keywords |
epigenetics; cancer; CpG islands; hypomethylation
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Citation |
Daura-Oller et al. Bioinformation 3(8): 340-343 (2009)
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Edited by |
P. Kangueane
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ISSN |
0973-2063
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Publisher |
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Copyright |
Publisher
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Copyright Transfer Agreement
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The authors of published articles in Bioinformation automatically transfer the copyright to the publisher upon formal acceptance. However, the authors reserve right to use the information contained in the article for non commercial purposes.
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License
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This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited.
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