Title

Authors

Takako Takai-Igarashi¹*, Ryo Akasaka², Kenji Suzuki², Takahisa Furukawa², Makiko Yoshida², Keisuke Inoue², Tomohisa Maruyama², Toshimasa Maejima², Masahiro Bando², Masakazu Takasaki², Miki Sakota², Maki Eguchi², Akihiko Konagaya³, Hiroya Matsuura³, Toyotaro Suzumura³, Hiroshi Tanaka¹
 

Affiliation

¹Graduate School of Biomedical Science, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8510 Japan; ²Educational Program for Bio-Medical OMICS Information, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-Ku, Tokyo, 113-8510 Japan; ³Interdsciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology, 4259 Nagatsuta-cho, Midori-ku, Yokohama, 226-8503 Japan 

Email

takai.com@mri.tmd.ac.jp; *Corresponding author

Phone

+81-3-5803-4763

Fax

+81-3-5803-0247

Article Type

Database

Date

Received March 04, 2011; Accepted March 07, 2011; Published March 26, 2011

Informatics for Integrating Biology and the Bedside (i2b2) is a database system to facilitate sharing and reuse of clinical patients’ data collected in individual hospitals. The i2b2 provides an ontology based object-oriented database system with highly simple and flexible database schema which enables us to integrate clinical patients’ data from different laboratories and different hospitals. 392 patients’ data including carcinoma and non-carcinoma specimens from cancer patients are transported from the Integrated Clinical Omics Database (iCOD) to the i2b2 database for a feasibility study to check applicability of i2b2 ontology and database schema on Japanese clinical patients’ data. No modification is required for the i2b2 data model to deal with Japanese characters. Some modification of ontology is required to integrate biomedical information extracted from the cancer patients’ data. We believe that the i2b2 system will be practical infrastructure to integrate Japanese clinical databases if appropriate disease ontology for Japanese patients is provided.  

Availability

http://bio-omix.tmd.ac.jp/disease/i2b2/

Citation

Takai - Igarashi et al. Bioinformation 6(2): 86-90 (2011)

Edited by

TW Tan

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.