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Title |
Gene Locater: Genetic linkage analysis software using three-point testcross |
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Authors |
Muhammad Zohaib Anwar1, Anoosha Sehar1, Inayat-ur-Rehman2, Mohammad Hassan Khalid1* |
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Affiliation |
1Comsats Institute of Information Technology, Islamabad, Pakistan; 2Department of Computer Science, Comsats Institute of Information Technology, Islamabad, Pakistan.
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hassankhalid@comsats.edu.pk; *Corresponding author
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Article Type |
Software |
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Date |
Received March 04, 2012; Accepted March 08, 2012; Published March 17, 2012
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Abstract |
Locating genes on a chromosome is important for understanding the gene function and its linkage and recombination. Knowledge of gene positions on chromosomes is necessary for annotation. The study is essential for disease genetics and genomics, among other aspects. Currently available software’s for calculating recombination frequency is mostly limited to the range and flexibility of this type of analysis. GENE LOCATER is a fully customizable program for calculating recombination frequency, written in JAVA. Through an easy-to-use interface, GENE LOCATOR allows users a high degree of flexibility in calculating genetic linkage and displaying linkage group. Among other features, this software enables user to identify linkage groups with output visualized graphically. The program calculates interference and coefficient of coincidence with elevated accuracy in sample datasets.
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Availability |
http://www.moperandib.com
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Keywords |
Coefficient of Coincidence, Double crossovers, Interference, Recombination Frequency, Single crossovers
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Citation |
Anwar et al.
Bioinformation 8(5): 243-245(2012) |
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Edited by |
P. Kangueane
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ISSN |
0973-2063
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Publisher |
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License |
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License. |