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Title

SALMONELLABASE - An online database of druggable targets of Salmonella species

 

Authors

Ophilia Benedict Pushpa & Muthaiyan Xavier Suresh*

 

Affiliation

Department of Bioinformatics, Sathyabama University, Jeppiaar Nagar, Rajiv Gandhi Salai, Chennai - 600 119

 

Email

xaviersuresh@gmail.com; *Corresponding author

 

Article Type

Database

Date

Received July 18, 2012; Accepted July 30, 2012; Published August 03, 2012

 

Abstract

Salmonellosis is one of the most common and widely distributed food borne diseases caused by Salmonella serovars. The emergence of multi drug resistant strains has become a threatening public health problem and targeting unique effectors of this pathogen can be considered as a powerful strategy for drug design. SalmonellaBase is an online web portal serving as an integrated source of information about Salmonella serovars with the data required for the structural and functional studies and the analysis of druggable targets in Salmonella. We have identified several target proteins, which helps in the pathogenicity of the organism and predicted their structures. The database will have the information on completely sequenced genomes of Salmonella species with the complete set of protein sequences of the respective strains, determined structures, predicted protein structures and biochemical pathways of the respective strains. In addition, we have provided information about name and source of the protein, Uniprot and Protein Data Bank codes and literature information. Furthermore, SalmonellaBase is linked to related databases and other resources. We have set up a web interface with different search and display options so that users have the ability to get the data in several ways. SalmonellaBase is a freely available database.

 

Availability

http://www.salmonellabase.com/

 

Keywords

SalmonellaBase, Database, Drug Design, Salmonella, Druggable Targets

 

Citation

Pushpa & Suresh, Bioinformation 8(15): 734-737 (2012)
 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.