BACK TO CONTENTS   |    PDF   |    PREVIOUS   |    NEXT

Title

Major bioactive metabolites from marine fungi: A Review

 

Authors

Saba Hasan*, Mohammad Israil Ansari1, Anis Ahmad2 & Maitreyi Mishra1

 

Affiliation

1Amity Institute of Biotechnology, AMITY University Uttar Pradesh, Lucknow Campus, Lucknow 226 028 INDIA; 2Department of Radiation Oncology, University of Miami, Miami, FL, USA

 

Email

shasan@lko.amity.edu; *Corresponding author

 

Article Type

Review

 

Date

Received March 22, 2015; Accepted March 26, 2015; Published April 30, 2015

 

Abstract

Biologists and chemists of the world have been attracted towards marine natural products for the last five decades. Approximately 16,000 marine natural products have been isolated from marine organisms which have been reported in approximately 6,800 publications, proving marine microorganisms to be a invaluable source for the production of novel antibiotic, anti tumor, and anti inflammatory agents. The marine fungi particularly those associated with marine alga, sponge, invertebrates, and sediments appear to be a rich source for secondary metabolites, possessing Antibiotic, antiviral, antifungal and antiyeast activities. Besides, a few growth stimulant properties which may be useful in studies on wound healing, carcinogenic properties, and in the study of cancers are reported. Recent investigations on marine filamentous fungi looking for biologically active secondary metabolites indicate the tremendous potential of them as a source of new medicines. The present study reviews about some important bioactive metabolites reported from marine fungal strains which are anti bacterial, anti tumour and anti inflammatory in action. It highlights the chemistry and biological activity of the major bioactive alkaloids, polyketides, terpenoids, isoprenoid and non-isoprenoid compounds, quinones, isolated from marine fungi.

 

Keywords

Marine fungi, bioactive metabolites, anti tumor; alkaloids, isoprenoids, polyketides.

 

Citation

Hasan et al. Bioinformation 11(4): 176-181 (2015)
 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.