Title

An analysis of phosphorylation sites in protein kinases from Leishmania

Authors

Sukrat Sinha & Shanthy Sundaram

Affiliation

Centre of Biotechnology, University of Allahabad, Allahabad, Uttar Pradesh – 211002 India

Email

Sukrat Sinha - E-mail: sukratsinha@gmail.com

Article Type

Hypothesis

Date

Received June 14, 2016; Revised July 4, 2016; Accepted July 5, 2016; Published July 26, 2016

Protein kinases are promising drug targets for Leishmaniasis. We have evaluated the phosphorylation potential of protein kinases in different species and strains of Leishmania. Phosphorylation potential of serine, threonine and tyrosine residues of kinases in Leishmania parasite were studied. The results indicate that some species specific residues of serine, threonine and tyrosine have a phosphorylation
potential of 1 suggesting that these residues are important target sites in protein kinases based anti-leishmanial therapies.

Keywords

phosphorylation sites, protein kinases, Leishmania

Citation

Sinha & Sundaram, Bioinformation 12(4): 249-253 (2016)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.