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Title

Impact of omega-3 fatty acids on calorie intake and certain anthropometric measurements in children with sickle cell disease in Saudi Arabia

 

Authors

Shahida Khan1*2, Ghazi Damanhouri1,3, Tahir Jameel4, Ashraf Ali1,2, Ahmad Makki1,2, Sarah Khan1,5, Ibtehal AlAnsari1, Saeed Halawani6, Fatma Zahrani7, Mohammad AlKazmi8, Ibrahim Ghita8

 

Affiliation

1Applied Nutrition Group, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia; 2Department of Medical Laboratory technology, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia; 3Department of Hematology, King Abdulaziz University hospital, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia; 4King Abdulaziz University hospital, Hematology department, Rabigh Branch, Kingdom of Saudi Arabia; 5Diabetes Unit, King Edward Memorial Hospital, 489, Sardar Moodliar Road, Rasta Peth, Pune, India; 6Department of Hematology and Immunology, Umm Al Qura University, Faculty of Medicine, Makkah, Kingdom of Saudi Arabia; 7Department of Pediatrics, King Abdulaziz University hospital, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia; 8Department of Hematology, Al-Noor Specialist hospital Makah, Kingdom of Saudi Arabia

 

Email

Dr. Shahida Aziz Khan - Email-sakhan01@kau.edu.sa; shahidakhan2009@gmail.com; *Corresponding author

 

Article Type

Research Article

 

Date

Received February 20, 2019; Accepted February 25, 2019; Published March 15, 2019

 

Abstract

The nutritional status and growth in children with SCD is compromised due to intake of diet that is low in calories as well as deficient in nutrients. Growth stunting and a low body mass index have been observed in these children. Some children exhibit pica which is an abnormal eating pattern by ingesting things other than food, like paper, wood etc. This also was found to correlate to lower hemoglobin values. Interventions with certain essential nutrients such as omega-3 fatty acids are known to benefit these children in terms of lowering their complications due to the disease. We therefore wished to see if omega-3 fatty acids exhibit positive effects on their nutritional intake and growth parameters too. Hence, we supplemented these children with omega-3 fatty acids for a period of six months. Both the male and female children with the disease significantly improved their calorific intake as well as body mass index. Also a lowering of pica status was distinctly observed.

 

Keywords

Diet, nutrition deficiency, disease severity, sickle cell disease, Saudi Arabia

 

Citation

Khan et al. Bioinformation 15(3): 189-193 (2019)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.