BACK TO CONTENTS   |    PDF   |   


Annotation of a hypothetical protein (WP_002969292.1) from Brucella abortus


Kanchan Rauthan, Divya Goel, Sudhir Kumar*



Department of Biotechnology, Hemvati Nandan Garhwal University, Srinagar Garhwal, Uttarakhand-246174, India


Email; *Corresponding author


Article Type

Research Article



Received April 1, 2019; Accepted April 17, 2019; Published April 30, 2019



Brucellosis is a zoonotic disease caused mainly by the bacteria belonging to the genus Brucella, most common of them is Brucella abortus. Genome sequencing of Brucella was completed in 2005. While majority of the proteins were assigned function, a large number of the peptides remained un-annotated and were referred as 'hypothetical'. These hypothetical proteins may contain crucial information about the biology and pathogenesis of the B. abortus. Therefore, it is of interest to annotate one such hypothetical protein as a multiple antibiotic resistance regulator protein, MarR. The physiological parameters, localization and the structural features were predicted for this protein which corroborated as the winged-helix type DNA-binding domain superfamily of transcription factors.



Annotation,  hypothetical protein, Brucella abortus



Rauthan et al. Bioinformation 15(5): 315-320 (2019)


Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.