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Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora



T Starlin1*, P Saravana Prabha1, B Allen Thayakumar2 & VK Gopalakrishnan1



1Department of Biochemistry and Bioinformatics, Karpagam Academy of Higher Education, Coimbatore, Tamilnadu, India 641 02; 2Cancer Biology Department, Mitra RxDx Inc. Woburn MA 01801, USA



Dr. Starlin Thangarajan - Ph: +91-9944698444; Email: starlinraj@gmail.com


Article Type

Research Article



Received May 22, 2019; Accepted June 3, 2019; Published June 15, 2019


Medicinal plants are boundless source of raw materials for the pharmaceutical. Identification of natural compounds from medicinal plant is helpful in the discovery of novel therapeutic agents. Tylophora pauciflora is a medicinal plant, which possess many biological activities such as antioxidant activity, anti-inflammatory activity and anti cancer activity. There is no GC-MS analysis reported on this plant. Thus, the present study is aimed to identify the present of phyto-chemical compounds from ethanolic extract of Tylophora pauciflora using GC-MS analysis. Results, the extract possess totally 14 bioactive compounds among that natural compound of n-hexadecanoic acid has highest % peak area and it have the variety of biological activities such as; anti-oxidant, 5-alpha-reductase-inhibitor, anti-fibrinolytic, hemolytic, antimicrobial activity, hypo-cholesterolemic, nematicide, pesticide, anti-androgenic flavor and hemolytic. It is concluded that the ethanolic extract of Tylophora pauciflora have biologically active compounds. In future by isolating and identifying, these compounds can be considered to treat the human disorders.



Tylophora pauciflora; ethanolic extract; GC-MS analysis; bioactive compounds



Starlin et al. Bioinformation 15(6): 425-429 (2019)


Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.