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Title

Association between the site of occurrence and pathological TNM staging in oral squamous cell carcinoma

 

Authors

R. Hannah* et al.

 

Affiliation

Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University 162, Poonamallee High Road, Chennai 600077

 

Email

R. Hannah: E-mail - rgracedentist@gmail.com; *Corresponding author

 

Article Type

Research Article

 

Date

Received October 7, 2020; Revised October 27, 2020; Accepted October 27, 2020; Published December 31, 2020

 

Abstract

Oral cancer is a worldwide health problem. Risk factors for oral squamous cell carcinoma (OSCC) are tobacco, alcohol, betel nuts, viral infection and dietary habit. The site of occurence of the OSCC differs substantially between different people groups mainly because of variations in the prevalence of risk factors. The prognosis varies based on the site. pTNM is also one of the most useful tools for the prediction of prognosis. Therefore, it is of interest to correlate the pTNM staging with the site of occurrence of the lesion using 36 OSCC case reports. The results revealed 36.11% of the lesion occurred in buccal mucosa. Stage III pTNM was most prevalent in buccal mucosa and tongue and Stage IV pTNM in the retromolar trigone region by significant association with p value < 0.05. Thus, we report that lesions occurring in the Retromolar region, tongue and buccal mucosa need to be given special attention, as they are associated with early metastasis and poor prognosis. Early diagnosis and appropriate treatment protocol will improve the quality of life for the patients.

 

Keywords

oral squamous cell carcinoma; TNM staging; buccal mucosa; prognosis; tongue.

 

Citation

Hannah et al. Bioinformation 16(12): 1019-1025 (2020)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.