Title

Modelling and docking analysis of a tumor target protein BAG3

Authors

Idris Mukhtar¹, Suleiman Oluwaseun Alakanse^2,*, Faoziyat Adenike Sulaiman², George Oche Ambrose², Ohanaka Judith Nkechinyere³, Adigun Adedayo²

Affiliation

¹School of Life Sciences University of Science and Technology of China Hefei, Anhui Province, People's Republic of China; ²Department of Biochemistry, University of Ilorin, Ilorin, Nigeria; ³Department of Biochemistry, Faculty of Natural and Applied Sciences, Nile University of Nigeria, Nigeria

Email

Suleiman Oluwaseun Alakanse - E-mail: oluwaseunalakanse@gmail.com

Article Type

Research Article

Date

Received February 8, 2020; Revised April 1, 2020; Accepted April 4, 2020; Published April 30, 2020

BCL2 associated anthanogene (BAG)s are class of proteins linked to tumorigenesis and apoptosis. Therefore, it is of interest to design and develop potent inhibitors for BAG. Hence, we report the optimal structure-based docked features of sesamolin with BAG3 with the acceptable ADMET properties for consideration in the context of Glioblastoma Multiforme treatment and therapy.

Keywords

Glioblastoma, BAG3, tumorigenesis, sesamolin, apoptosis.

Citation

Mukhtar et al. Bioinformation 16(4): 351-358 (2020)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.