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Inhibitory studies of HepG2 and human immune cells using Solanum nigrum


Anbazhagan Ganesh Kumar1, Giridharan Bupesh3,5,*, Palanandi Sankarganesh 2,*, Sakthivel Vasanth3, Siddan Nandagopal4 and Baby Joseph5



1Department of Microbiology, Hindustan College of Arts and Science, Padur, Chennai - 603 103, Tamil Nadu, India; 2*& 5Center for Research and Consultancy, Hindustan Institute of Technology and Science, Padur, Chennai-603103 Tamil Nadu, India; 3Research and Development
Wing, Sree Balaji Medical College and Hospital, Bharath Institute of Higher Education & Research, Chromepet - 600 042, Tamil Nadu, India; 4Department of Botany, Government Arts College, Hosur 635001, Tamil Nadu, India. 5Department of Forest Science, School of Science, Nagaland University (Central), Lumami, Zenheboto, Nagaland-798627, India



*Corresponding authors: bupeshgiri55@gmail.com; bilisankar@gmail.com


Article Type

Research Article



Received January 1, 2020; Revised June 3, 2020; Accepted June 5, 2020; Published July 31, 2020



It is of interest to document the inhibitory studies of HepG2 and human immune cells using Solanum nigrum. We have assessed the effect of ethanolic extract from Solanum nigrum for antiproliferative on HepG2 and on human PBMC. Treatment with Solanum nigrum separates the cells that are estimated by 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide measure. Results indicated improved cytotoxicity with expanding concentrations of extract.



Inhibitory studies, HepG2, human immune cells, Solanum nigrum



Kumar et al. Bioinformation 16(7): 525-531 (2020)


Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.