Title

Antimicrobial activity of silymarin mediated zinc oxide and hydroxy apatite nanoparticles against oral pathogens

Authors

S. Aravind Kumar¹, S. Rajeshkumar² *, SP Saravana Dinesh¹, Ashwin Mathew George¹, Ravindra Kumar Jain¹

Affiliation

¹Department of Orthodontics, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai - 600077, Tamilnadu, India; ²Nanobiomedicine Lab, Department of Pharmacology, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai - 600077, Tamilnadu, India

Email

Dr. S. Rajeshkumar - E-mail: ssrajeshkumar@hotmail.com, *Corresponding author

Article Type

Research Article

Date

Received September 17, 2020; Revised September 28, 2020; Accepted September 28, 2020; Published November 30, 2020

The nanoparticles such as hydroxyapatite, zinc oxide, titanium dioxide and zirconium nanoparticles have application in dentistry. Therefore, it is of interest to document the antimicrobial activity of silymarin mediated zinc oxide and hydroxy apatite nanoparticles against oral pathogens. Hence, we synthesized hydroxyapatie and zinc oxide nanoparticles with silymarin and characterized by UV-visible spectrophotometer. Data shows that silymarin mediated HAP and ZnO nanoparticles have antimicrobial activity against oral pathogens such as Pseudomonas sp, Staphylococcus aureus, Streptococcus mutans, Enterococcus faecalis and Candida albicans.

Keywords

Hydroxyapatite nanoparticles, green synthesis, silymarin, zinc oxide nanoparticles, oral pathogens.

Citation

Aravind Kumar et al. Bioinformation 16(11): 863-868 (2020)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.