Title

Molecular docking analysis of compounds from Justica adhatoda L with glycogen synthase kinase-3 β

Authors

Selvaraj Jayaraman¹, Vishnupriya Veeraraghavan², Radhika Nalinakumari Sreekandan^3, Surapaneni Krishna Mohan⁴, Sumetha Suga Deiva Suga⁵, Devakumar Kamaraj⁶, Sonaimuthu Mohandoss⁷, Ponnulakshmi Rajagopal^8*

Affiliation

^1,2Department of Biochemistry, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600 077, India; ³Department of Clinical Skills & Simulation, Panimalar Medical College Hospital & Research Institute, Varadharajapuram, Poonamallee, Chennai - 600 123; ⁴Department of Biochemistry and Department of Clinical Skills & Simulation, Panimalar Medical College Hospital & Research Institute, Varadharajapuram, Poonamallee, Chennai - 600 123; ⁵Department of Microbiology, Panimalar Medical College Hospital & Research Institute, Varadharajapuram, Poonamallee, Chennai - 600 123; ⁶Department of Pharmacology, Panimalar Medical College Hospital & Research Institute, Varadharajapuram, Poonamallee, Chennai - 600 123; ⁷School of Chemical Engineering, Yeungnam University, Gyeongsan, Gyeongbuk-do, 38541, Republic of Korea; ⁸Central Research Laboratory, Meenakshi Academy of Higher Education and Research (Deemed to be University), West K. K. Nagar, Chennai-600 078, India

Email

 Dr. Ponnulakshmi Rajagopal, Email: ramgslaks@gmail.com; Corresponding author*

Article Type

Research Article

Date

Received September 11, 2020; Revised October 22, 2020; Accepted October 22, 2020; Published November 30, 2020

Type 2 diabetes mellitus (T2DM) is linked with Glycogen synthase kinase-3 β.Therefore, it is ofinterest to document molecular docking analysis data of compounds from Justica adhatoda L with glycogen synthase kinase-3 β. We report the binding features of ethambutol, pyrazinamide, stigmasterol and vasicoline with GSK-3 β.

Keywords

Type 2 Diabetes mellitus, Justica adhatoda L, molecular docking.

Citation

Jayaraman et al. Bioinformation 16(11): 893-899 (2020)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.