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Title

Information on dysregulation of microRNA in placenta linked to preeclampsia
 

Authors

Abdifatah Mohamed Nuh1,2, Yan You1,2 & Min Ma1,2

 

Affiliation

1Department of Obstetrics, Affiliated Hospital of Yangzhou University, Yangzhou, Jiangsu Province, 225000, China; 2Yangzhou University Medical College, Yangzhou, Jiangsu Province, 225000, China;

 

Email

E-mail: mamin@yzu.edu.cn

 

Article Type

Research Article

 

Date

Received December 17, 2020; Revised January 30, 2020; Accepted January 31, 2020, Published January 31, 2021

 

Abstract

MicroRNAs are single-stranded, non-coding RNA molecules, regulate gene expression at the post-transcriptional level. They are expressed in the human body and have a significant impact on the different processes of pathological illness. A developing placenta undergoes a series of stages after successful fertilization, such as cell division, migration, adhesion, apoptosis, and angiogenesis. MicroRNAs dysregulation in placenta has been linked to pregnancy-related complications such as preeclampsia. Therefore, it is of interest to document known information (list of microRNA) on this issue in the development of biological tools for diagnosis, treatment and prevention of the disease.

 

Keywords

MicroRNAs; preeclampsia; pregnancy; placenta; trophoblast.

 

Citation

Mohamed Nuh et al. Bioinformation 17(1): 240-248 (2021)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.