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Myeloperoxidase and troponin T are linked with myocardial infarction among young Indians


Anoop Jaiswal1, Beenu Doctor2, Manish Kumar Verma3 & Amrita Vamne1,*



1Department of Biochemistry Index Medical College, Malwanchal University Indore, MP, India; 2Department of Biochemistry, Moti Lal Nehru Medical College, Prayagraj, UP, India; 3Department of Biochemistry, GSVM Medical College, Kanpur, UP, India; *Corresponding author



Anoop Jaiswal E-mail: biochemanoop11@gmail.com Beenu - E-mail:  dbeenu.santosh@gmail.com Manish Kumar Verma - E-mail: manishverma8919@gmail.com Amrita Vamne - E-mail: avamne@gmail.com


Article Type

Research Article



Received November 21, 2021; Revised December 23, 2021; Accepted December 23, 2021, Published January 31, 2022



It is of interest to document the correlation of myeloperoxidase (MPO) and Troponin T (TnT) in young Indian patients with myocardial infarction using epidemiological data. A study with 220 (110 case and 110 control) participants with Acute Coronary Syndrome (both males and females) was completed. Patients were identified using a pre-designed PROFORMA at the OPD and IPD of the Medicine Department at the Index Medical College & Hospital, Malwanchal University and Moti Lal Nehru Medical College and Swaroop Rani Nehru Hospital in India. MPO and TnT were measured using the Sandwich ELISA (Sandwich Enzyme linked immunosorbent Assay) kit. TnT (pg/ml) (Mean SD) were high in the case group than control 134.7 8.57 vs 96.6 2.82; F = 145.9; t = 44.3; p < 0.01). Moreover, MPO was 3-fold high in case group than control (15730.1 and 42.414.82, respectively). The differences was found statistically significant (p<0.001). This suggests a link between TnT and MPO among young Indian patients with myocardial infarction.



Myocardial infarction, myeloperoxidase, Troponin T, Sandwich ELISA



Jaiswal et al. Bioinformation 18(1): 66-71 (2022)


Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.