Title
In vitro anti-inflammatory and wound healing properties of Andrographis echioides and Andrographis paniculata
Authors
Kaviya Selvaraj, R. Gayatri Devi*, J. Selvaraj & A. Jothi Priya
Affiliation
Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Science (SIMATS), Saveetha University, Chennai 600077, India; *Corresponding author
R. Gayatri Devi – E-mail: gayatridevi@saveetha.com
Kaviya Selvaraj – E-mail: kaviyaselvaraj2003@gmail.com
J Selvaraj – E-mail: selvarajj.sdc@saveetha.com
A. Jothi Priya – E-mail: jothipriya.sdc@saveetha.com
Article Type
Research Article
Date
Received January 11, 2022; Revised April 30, 2022; Accepted April 30, 2022, Published April 30, 2022
Abstract
Andrographis echioides (L.) is an annual herbaceous plant in the family Acanthaceae. Anti-inflammatory is the property of a substance or treatment that reduces inflammation or swelling. Antioxidants are substances that can prevent or slow damage to cells caused by free radicals, unstable molecules that the body produces as a reaction to environmental and other pressures. They are sometimes called “free-radical scavengers. Therefore, it is of interest to analyse the anti-inflammatory and antioxidant properties of Andrographis echioides and Andrographis paniculata. Protease inhibitor activity was done by bovine serum albumin was added to 100μl of plant sample with increase in concentrations (100-500μg/ml). In vitro antioxidant activity was done by DPPH free radical scavenging assay. 200 μL of 0.1 mM DPPH prepared in methanol was added to 100 μL of the plant extract with increase in concentration. Based on the results from the present study, it can be concluded that A.echioides is found to be a good natural antioxidant source and A. paniculata is found to be a good anti-inflammatory source. However, both the plant A. echioides and A.paniculata have these properties. Data shows that both A. echioides and A. paniculata have potential anti-inflammatory and antioxidant activity which could be due to the presence of bioactive compounds present in the plant extracts.
Keywords
Andrographis echioides, Andrographis paniculata, anti-inflammatory, antioxidant, wound healing property, innovative technology
Citation
Selvaraj et al. Bioinformation 18(4): 331-336 (2022)
Edited by
P Kangueane
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
