Title

A review on hypo-cholesterolemic activity of Nigella sativa seeds and its extracts

Authors

Karmegam Uma Maheswari^1,2,*, K. Dilara¹, S. Vadivel², Priscilla Johnson¹ & Selvaraj Jayaraman³

Affiliation

¹Department of Physiology, Sri Ramachandra Medical College and Research Institute (SRMC & RI), Porur, Chennai- 600116, India; ²Department of Physiology, Karpaga Vinayaga Institute of Medical Education and Research, Madhuranthagam, Chengalpet-603308, Tamil Nadu, India; ³Department of Biochemistry, Saveetha Dental College & Hospital, Saveetha Institute of Medical & Technical Sciences, Chennai 600077, India; *Corresponding author

Email

K. Uma Maheswari - E-mail: umakarmegam@gmail.com

K. Dilara - E-mail: dilarak@sriramachandra.edu.in

S. Vadivel - E-mail: drsvadivel2012@gmail.com

Priscilla Johnson - E-mail: priscillajohnson@sriramachandra.edu.in

Selvaraj Jayaraman - E-mail: selvarajj.sdc@saveetha.com

Article Type

Research Article

Date

Received March 1, 2022; Revised April 30, 2022; Accepted April 30, 2022, Published April 30, 2022

Nigella sativa (N. sativa) (Family Ranunculaceae) is a popular therapeutic herb in many parts of the world. It is widely used in traditional medical systems such as Unani, Ayurveda and Siddha. Seeds and oil have a long history of folkloric use in many medicinal and culinary systems. The seeds of N. sativa have long been used to treat a variety of illnesses and disorders. Studies on N. sativa and its therapeutic potential have been investigated. This includes anti-diabetic, anticancer, immune-modulatory, analgesic, antimicrobial, anti-inflammatory, spasmolytic, bronchodilator, hepato-protective, renal protective, gastro-protective, antioxidant properties, and several others. Nigella sativa contains thymoquinone. This is a bioactive component of the essential oil with medicinal benefits. Therefore, it is of interest to report a comprehensive data on the therapeutic usefulness of N. sativa in hypo-cholesterolemic activity.

Keywords

Nigella sativa, black seed, hypo cholesterolemic activity

Citation

Uma Maheswari et al. Bioinformation 18(4): 343-348 (2022)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.