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Sequence to predicted structure and function for DHX8


Muhammed A Bakhrebah1, Majed S Nassar1,*, Fahad M Alhoshani1, Abdulkhaliq Munawir Alanazi2 & Saeed A Asiri3



1Life Science and Environment Research Institute, King Abdulaziz City for Science and Technology (KACST), P.O. Box 6086, Riyadh 11442, Kingdom of Saudi Arabia; 2Department of Respiratory Services, Ministry of National Guard Hospital and Health affairs (MNGHA), P.O. Box 22490, Riyadh, Kingdom of Saudi Arabia; 3Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Najran University; *Corresponding author



Muhammed A Bakhrebah - E-mail: mbakhrbh@kacst.edu.sa
Majed S Nassar - E-mail: mnassar@kacst.edu.sa
Fahad M Alhoshani - E-mail:fhoshani@kacst.edu.sa
Abdulkhaliq Munawir Alanazi - E-mail:alanaziab33@ngha.med.sa
Saeed A Asiri - E-mail:saaasiri@nu.edu.sa


Article Type

Research Article



Received March 1, 2022; Revised April 30, 2022; Accepted April 30, 2022, Published April 30, 2022



DEAH-box helicase 8 (DHX8) is a protein coded by the DHX8 gene in humans. Available information on the sequence to structure to function for this protein is limited in the literature. Therefore, it is of interest to document insights gleaned from the sequence to structure to functional analysis of the DHX8 protein using known software tools such as SMART, Prosite, Pfam, PANTHER, and InterProScan. We also present the predicted preliminary structure data for the protein to glean structure based functional insights.



DHX8, Pfam, Inter Pro Scan beta turn, α-helix, SMART, Prosite, PANTHER, Ramachandran plot, hydrophobicity and antigenic region



Bakhrebah et al. Bioinformation 18(4): 411-419 (2022)


Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.