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Title

Salivary retention of silver diamine fluoride

Authors

Zohra Jabin, V. Vishnu Priya & Iffat Nasim

 

Affiliation

Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India; *Corresponding author

 

Email

Zohra Jabin - E-mail: drzohrajabin@gmail.com; Phone: +91 9871933858

V. Vishnu Priya - E-mail: Vishnupriya@saveetha.com

Iffat Nasim - E-mail: iffatnasim@saveetha.com

 

Article Type

Research Article

 

Date

Received March 1, 2022; Revised April 30, 2022; Accepted April 30, 2022, Published April 30, 2022

 

Abstract

The topically applied fluorides are efficacious in both prevention against caries attack and inhibition of virulent bacteria. The purpose of this clinical trial was to assess the fluoride concentration in saliva before and after 38% SDF, 5% NaF and 1.23% ApF gel application on enamel and duration of its availability at different time intervals. The present randomized clinical trial was conducted among 60 healthy children aged between 6-12 years where at baseline the participants were instructed to spit for 2 min in sterile containers and the first saliva sample (S1) was taken. The participants were then randomly allocated into 3 different groups in which 38% Silver diamine fluoride, 5% Sodium fluoride and 1.23% ApF gel were applied respectively. The second saliva sample (S2) was collected after 5 min and patients were called after 1 hour for third saliva sample collection. The fluoride concentration was measured in the salivary samples. ANOVA test was used for evaluation and chi square t test was conducted for comparison of 3 groups. The fluoride concentration is comparatively slightly higher for the group receiving SDF than NaF and ApF at baseline, 5 min and 1 hour time interval but is not statistically significant. The mean scores of Fluoride concentration of the three groups were statistically significant at 5 min (F=63.556, p<0.0005) and 1 hour time interval (F=17.577, p<0.0005). Slightly increased salivary fluoride retention was observed post SDF application at 5min and 1 hour time interval when compared to Na F and ApF gel application. The present trial also concluded that topical fluoride application increases fluoride bioavailability in saliva thereby increasing tooth remineralization.

 

Keywords

Silver Diamine Fluoride, fluoride retention, enamel demineralization, primary teeth, saliva

 

Citation

Jabin et al. Bioinformation 18(4): 420-424 (2022)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.