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Title

Comparative structural and functional analysis of the PGU1 protein from Saccharomyces bayanus with other Saccharomyces species

Authors

Chennupati Vidyasagar1, Pasupuleti Santhosh Kumar2, Poondla Vijayakumar1, Saggam Alekya1, Katike Umamahesh1 & Obulam Vijaya Sarathi Reddy1,*

 

Affiliation

1Department of Biochemistry, S.V.University, Tirupati 517 502, India; 2Department of Biotechnology, SVIMS University, Tirupati 517 502, India; *Corresponding author

 

Email

Chennupati Vidyasagar - E-mail: chennupati.vidyasagar@gmail.com

Pasupuleti Santhosh Kumar E-mail: santhosh.biotech08@gmail.com

Poondla Vijayakumar - E-mail: vijaykumar4p@gmail.com

Saggam Alekya - E-mail: saisekali2008@gmail.com

Katike Umamahesh - E-mail: u.mahesh90@yahoo.com

Obulam Vijaya Sarathi Reddy - E-mail: ovsreddy@yahoo.com

 

Article Type

Research Article

 

Date

Received April 2, 2022; Revised May 31, 2022; Accepted May 31, 2022, Published May 31, 2022

 

Abstract

An endo-poly-galacturonase (PGU1) gene product is responsible for the pectolytic activity in Saccharomyces bayanus. Therefore, it is of interest to document the comparative structural and functional analysis of the PGU1 protein from Saccharomyces bayanus with those in other Saccharomyces related species. The molecular docking analyses of pectin with the different homology models of PGU1 protein from several Saccharomyces species are reported.

 

Keywords

Saccharomyces bayanus; PGU1; Pectin; Homology modelling; Molecular docking

 

Citation

Vidyasagar et al. Bioinformation 18(5): 464-469 (2022)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.