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Title

Molecular docking analysis of VEGF with compounds from tomato

Authors

Madhan Krishnan1,*, Shyamaladevi Babu1, Suni Ann Thomas2, Jaya Senthilnathan Surulivel3, Kavitha Ayyanar4

 

Affiliation

1Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, chengalpattu District, Tamilnadu, India; 2Department of Biochemistry, Al Azhar Medical College Thodupuzha, Kumaramangalam, Kerala, India; 3Department of General Medicine, Vels Medical College & Hospital, Vels Institute of Science Technology & Advance Studies (VISTAS), Chennai, Tamilnadu, India, 4Department of Biochemistry, Vels Medical College & Hospital, Vels Institute of Science Technology & Advance Studies (VISTAS), Chennai, Tamilnadu, India; *Corresponding author

 

Email

Madhan Krishnan - Email: kmadhan91@gmail.com

Shyamaladevi Babu - Email: syamdevi06@gmail.com

Suni Ann Thomas Email: sunisarith@gmail.com

Jaya Senthilnathan S Email: sjayasenthilnathan@gmail.com

Kavitha Ayyanar Email: kaviaynam@gmail.com

 

Article Type

Research Article

 

Date

Received April 2, 2022; Revised May 31, 2022; Accepted May 31, 2022, Published May 31, 2022

 

Abstract

Vascular endothelial growth factor (VEGF) is linked with Non-small cell lung carcinoma (NSCLC). Therefore it is of interest to document data on the molecular docking analysis of VEGF with compounds from tomato for consideration drug discovery. Data shows that compounds Kaempferol-3-O, Quercetin, Naringenin & Rutin show optimal binding.

 

Keywords

Molecular docking, VEGF, lung cancer, tomato

 

Citation

Krishnan et al. Bioinformation 18(5): 478-481 (2022)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.