(©) 2001-2009 Biomedical Informatics
The critical issue
in the design of a T-cell epitope vaccine is the identification of
peptide cocktails with proven ability to bind all or most known class
I or class II MHC molecules.
Therefore, MHC-peptide binding is a rate limiting
step in epitope selection. However,
MHC molecules are highly polymorphic among ethnic population.
Hence, the selection of peptide by MHC
molecules is specific and combinatorial. Here, we provide a prediction method for
MHC-peptide binding. The method is made available through
a web prediction server.
last updated October 16, 2009; contacts: E-mail:
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(©) 2001-2009 Biomedical Informatics Network