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Title

Differential prolactin levels among male and female patients with thyroid related complains in the Hail regions of Saudi Arabia

 

Authors

Gamal Mohamed Elawad Ahmed1, Jerold Casem Alcantara1, Samir Abdulkarim Alharbi2, Waled
Mansi Alshammari3, Fawaz Dabae Alshammari1,*, Ibtihag Siddig Elnaem4, Abdelmuhsin Omer
Ahmed Hassan1, Khalid Sowilih Alrashedi5, Ahmed Abdulaziz Al Tayyar5, Turky Ali K. Alreshidi5

 

Affiliation

1Department of Clinical Laboratory Science, College of Applied Medical Sciences, University of Hail, Saudi Arabia; 2Department of Clinical Laboratory Science, College of Applied Medical Sciences, Shaqra University, Saudi Arabia; 3Hail King Khaled Hospital, Hail, Saudi Arabia; 4College of Dentistry, University of Hail, Saudi Arabia; 5Hail Regional Laboratory, Hail, Saudi Arabia;

 

Email

Fawaz Dabae Alshammari E-mail:fawazaboff@gmail.com; *Corresponding author

 

Article Type

Research Article

 

Date

Received September 14, 2019; Revised September 27, 2019; Accepted September 30, 2019; Published October 9, 2019

 

Abstract

Thyroid diseases are caused by autoimmunity due to hormone imbalance both in male and female patients. Therefore, it is of acute importance to measure, analyze and compare thyroid hormone levels among populations with thyroid-related complications. Hence, we examined 202 male and female thyroid patients in the Hail regions of Saudi Arabia and estimated their hormone levels. Blood samples were collected from patients and processed for the hormonal profiling such as prolactin, luteinizing hormone (LH), FSH, free T3 (FT3), free T4 (FT4) and TSH3. Further, measurement of thyroid gland size in the Hail population was also completed. Results of our study showed a significant difference in the level of prolactin between male and female patients. Other hormones are namely luteinizing hormone (LH), FSH, free T3 (FT3), free T4 (FT4), TSH3 did not show any significant difference between male and female patients with thyroid disorder.
Thus, the levels of the majority of hormones, namely luteinizing hormone (LH), FSH, free T3 (FT3), free T4 (FT4), and TSH3, except prolactin, did not differ significantly between male and female thyroid patients. Validation of the observation using large scale population size is warranted in future investigations.

 

Keywords

FSH, hormones, luteinizing hormone, prolactin, T3, T4, thyroid disorders, TSH

 

Citation

Elawad Ahmed et al. Bioinformation 15(9): 633-639 (2019)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.