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Insights from the cDNA and EST analysis of Antrodia cinnamomea


Jing Li1, Yanling Liu1, Richard Yankey1, 2, Dongmei Lin1 & Zhanxi Lin1,*



1National Engineering Research Center of JUNCAO Technology, Fujian Agriculture and orestry University, Fujian, Fuzhou 350002, PR China; 2Life Science College, Fujian Agriculture and Forestry University, Fujian, Fuzhou 350002, PR China; *Corresponding author



Zhanxi Lin Email ID: lzxjuncao@163.com;


Article Type

Research Article



Received July 21, 2020; Revised December 31, 2020; Accepted January 26, 2020, Published January 31, 2021



It is of interest to document the insights gleaned from the cDNA and EST analysis of Antrodia cinnamomea (a fungal species). Hence a library of sequences was constructed and analysed using standard procedures to gain new insights. Therefore, 65 ESTs, with size ranging from 300-2000 bp, were constructed. This included 46 ESTs with definite annotation, 18 ESTs were hypothetical and 1 new protein derived from BLAST analysis. We assigned 227 Gene Ontology terms linked to cell composition, transport, catalytic activity, and regulation functions in these sequences. Moreover, 56 matching genes were found in 8 Kyoto Encyclopedia of Genes and Genomes pathways. Data also showed 271 SSRs from Antrodia cinnamomea ESTs with an occurrence frequency of 96.82%. The STRING data analysis showed 29 genes encoded enzymes highly involved in protein-to-protein interactions linked to expression of regulation function. Thus, we documented some insights from the cDNA and EST analysis of Antrodia cinnamomea for further data mining.



Antrodia cinnamomea; genome wide analysis; cDNA; EST; GO functional annotation;



Li et al. Bioinformation 17(1): 109-118 (2021)


Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.