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Comparative evaluation of ropivacaine and lidocaine as dental pulp anaesthesia


Vijayapriyangha Senthilkumar & Sindhu Ramesh



Department of Conservative Dentistry and Endodontics Saveetha Dental College, Saveetha Institute Of Medical And Technical Science Chennai, India;



E-mail: vijayapriyangha@gmail.com; Telephone Number: 9444622511. *Corresponding author - Sindhu Ramesh - E-Mail: drsinsushil@gmail.coml; Telephone Number: +919840136543


Article Type

Research Article



Received December 29, 2020; Revised January 15, 2020; Accepted January 26, 2020, Published January 31, 2021



Root canal therapy linked to pulpal diseases or trauma is common in modern dental care. The 2% Lidocaine which is considered as the gold standard has some drawbacks in pulpal anaesthesia. Ropivacaine has beneficial anaesthetic effects on pulpal anaesthesia. Therefore, it is of interest to compare and evaluate the pulpal aesthetic effect using 0.5% Ropivacaine and 2% Lidocaine in symptomatic irreversible pulpitis. A double blinded randomized controlled clinical trial consisting of 110 lower molar and premolar tooth with irreversible pulpitis cases for root canal therapy were selected and randomly divided into 2 groups. Group A: 2% lidocaine with epinephrine and Group B: 0.5% ropivacaine. The pulp sensibility tests with heat test, cold test and electric pulp test were completed. The preoperative pain score was measured with Visual Analogue Scale (VAS) pain scale. Classical inferior alveolar nerve block (IANB) technique was given to all patients by a single operator. Subjects were asked for lip numbness and presence or absence of lip numbness. Postoperative pain scores were recorded during access opening and on placing files in the canal. There is no statistical difference between the groups during pre operative conditions. The mean pain scores within group A and group B is recorded. The difference was found to be statistically significant with p value ≤ 0.05. Significant difference between the mean values after and before the treatment is observed. However, there is no statistical significance between the mean pain scores between the access and pulp. The 0.5% Ropivacaine and 2% Lidocaine with epinephrine does not have any significant difference during access opening. However, 0.5% Ropivacaine groups were effective while placing the file in the canal. Thus, 0.5% Ropivacaine showed better results even though it was not statistically significant for further consideration in this context.



Inferior alveolar nerve block; Local anesthesi; Pulpal anesthesia; Ropivacaine; Symptomatic Irreversible pulpitis.



Senthil Kumar & Ramesh, Bioinformation 17(1): 229-239 (2021)

Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.