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Treatment of periodontal disease using xanthan based chlorhexidine gel


Abhishek Gautam, Kumar Manish* & Raju Kumar



1Department of Dentistry, Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar, India; 2Indian Agricultural Statistics Research Institute, New Delhi, India;



Abhishek Gautam - Email: dr.abhi90@gmail.com; Kumar Manish - Email: drkmanish@gmail.com; Raju Kumar - raju.iasri@gmail.com


Article Type

Research Article



January 21, 2021; Revised February 20, 2020; Accepted February 27, 2020, Published February 28, 2021



People of all ages are suffering from periodontal disease. It causes indirect damage in the oral cavity. It is of interest to evaluate the efficacy of xanthan-based chlorhexidine gel (Xan-CHX) in patients with mild-severe chronic periodontitis. Five patients with 60 sites were divided in two groups. Group A (treated with SRP) and group B (treated with Chlosite i.e., SRP + CHL). The recorded clinical parameters were Plaque index (PI), Gingival index (GI), Bleeding index (BI), and Clinical attachment Level (CAL) with sub gingival plaque subjected to microbial analysis. Significant reduction was observed in both groups. However, group B (treated with Chlosite i.e., SRP + CHL) showed statistically significant improvement on above mentioned parameters as compared to group A. Data suggest that in the treatment of periodontal disease (viz. PI, GI, BI and CAL) combination of SRP and Chlosite showed added benefits over only SRP.



Chlosite; chronic periodontitis; xanthan - based chlorhexidine.



Gautam et al. Bioinformation 17(2): 326-330 (2021)


Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.