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Molecular docking analysis of quercetin with known CoVid-19 targets



Sridevi Chandra Subash Chandran1, Ireen Christopher2,3, Aishwariya Sounderraajan2,3, Viji Murugesan2,3, Indu Sabapathy2,3, Vijayalakshmi Periyasamy2,3& Rajalakshmi Manikkam2,3,4*



1Sastra Deemed University, Tirumalaisamudram, Thanjavur – 613401, India; 2Department of Biotechnology and Bioinformatics, Holy Cross College (Autonomous), Tiruchirappalli, Tamil Nadu, India, 3DBT-BIF Centre, Holy Cross College (Autonomous), Tiruchirappalli, Tamil Nadu, India, 4Department of Zoology, Holy Cross College (Autonomous), Tiruchirappalli, Tamil Nadu, *- Corresponding author.



S. Sridevi Chandra – Email: sri.chandra29@gmail.com

C. Ireen – Email: ireentrichy@gmail.com

S. Aishwariya– Email: aishu21121999@gmail.com

M. Viji- Email: vijimurugesan692@gmail.com

P. Vijayalakshmi- Email: pvijibi@gmail.com

S. Indu- Email: sabaindhu2010@gmail.com

M. Rajalakshmi- Email: mdrajimd@gmail.com


Article Type

Research Article



Received November 1, 2023; Revised November 30, 2023; Accepted November 30, 2023, Published November 30, 2023



Combat and care during CoVid-19 was non-trivial. Therefore, it is of interest to use the pharmacologically active plant component quercetin for the treatment of CoVid-19. Quercetin exhibits favourable ADMET values and abides by Lipinski's rule of five. When quercetin and remdesivir were positioned in relation to the CoVid-19 targets, quercetin exhibited a greater propensity for binding and H-bond interaction in their molecular interactions. Thus, the quercetin molecule can be used to manage CoVid-19.



CoVid-19, quercetin, remdesivir, ADMET, docking.



Subash Chandran et al. Bioinformation 19(11): 1081-1085 (2023)


Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.