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Biochemical analysis of methanolic extract from Evolvulus alsinoides



Karnam Nithya1*, Rajaram Siddaraman2, PP Sheelajoice3, Mani Rajarathinam4 & Vurimi Bhopal Chandra5



1Department Of Pharmacology, Vinayaka Missions University, Salem, Chinna Seeragapadi, Salem - 636308, Tamilnadu, India; 2Department of Pharmacology, VMKV Medical College, Chinna Seeragapadi, Salem - 636308, Tamil Nadu, India; 3Department Of Physiology, VMKV Medical College, Chinna Seeragapadi, Salem - 636 308, Tamil Nadu, India; 4Department Of Pharmacology, GMKMC Medical College, Shavapet Salem 636002, Tamil Nadu, India; 5Department of Pharmacology, Narayana Medical College, Nellore - 524 003, AP, India;



Karnam Nithya - E-mail - nithyasree13@gmail.com

Rajaram Siddaraman - E-mail - drrjrm@gmail.com

PP Sheelajoice - E-mail - sheelapaul05@gmail.com

Mani Rajarathinam - E-mail - drmanivp@gmail.com

Vurimi Bhopal Chandra - E-mail - bhopalchandra@gmail.com


Article Type

Research Article



Received December 1, 2023; Revised December 31, 2023; Accepted December 31, 2023, Published December 31, 2023



Evolvulus alsinoides is a medicinal plant in the Convolvulaceae family. Traditionally, it is used for different ailments in India and in several other countries. It has a variety of pharmacological qualities, including those that aid wound healing, hepato-protection, cardio-protection, anti-diabetic action, asthma, and epilepsy, memory and learning, and neuroprotection. The whole plant is utilized in Ayurvedic medicine to treat neurological disorders, including amnesia, and it is called the brain tonic by them. Therefore, the use of GC-MS in phytochemical research and chemotaxonomic investigations of medicinal plants containing physiologically active components is critical. Hence, the various secondary metabolites from the methanolic extract of E. alsinoides were analyzed using GC-MS technique. The methanolic extract of E. alsinoides yielded ten compounds. All ten compounds showed the highest number of hits. Those with the highest concentration were chosen to identify the qualitative compound. All compounds are non-toxic. Molecules with specific properties are capable of modulating a variety of proteins, including some enzymes. Thus, these molecules are potential hit-to-lead molecules in preclinical studies.



Phytochemistry, Evolvulus alsinoides, convolvulaceae, GCMS



Nithya et al. Bioinformation 19(12): 1173-1178 (2023)


Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.