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Title

Anti-inflammatory and antioxidant effects of hydro-alcoholic extract of Dicliptera cuneata Nees aerial parts

 

Authors

Parepalli Suresh, VP Karthik* & Durai Pandian Chamundeeswari

 

Affiliation

Department of Pharmacology, SRMC & RI, Sri Ramachandra Institute of Higher Education and Research-DU, Porur, Chennai - 600116, Tamil Nadu, India;

 

Email

VP Karthik E-mail: dr_karthikvp@yahoo.co.in

P Suresh E-mail: parepallisuresh@sriramachandra.edu.in

 

Article Type

Research Article

 

Date

Received December 1, 2023; Revised December 31, 2023; Accepted December 31, 2023, Published December 31, 2023

 

Abstract

Dicliptera cuneata Nees is a traditional medicinal plant but its extract or phytochemicals are less known. Therefore, it is of interest to investigate the anti-inflammatory and antioxidant effects of aerial part hydroalcoholic extract of Dicliptera cuneata Nees. Hence, we used protein denaturation assay, FRAP assay, Nitric oxide and peroxide scavenging assays methods following standard developed techniques. The hydro-alcoholic extract exhibited dose-dependent effectiveness in all the assays and showed maximum efficacy in the assays at higher doses selected. Data shows that hydroalcholic extract of Dicliptera cuneata Nees showed anti-inflammatory and antioxidant properties in in vitro settings. It should be noted that more data is needed to further develop the extract into suitable formulations.

 

Keywords

Dicliptera cuneata Nees; acanthaceae; protein denaturation; oxidation; free radicals

 

Citation

Suresh et al. Bioinformation 19(12): 1193-1196 (2023)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.