Title

Management of peri-implantitis using local drug delivery among Indian patients

Authors

Shilpi Khare^1,*, Hitika P Doda², Vanya Dubey³, Shreyansh Sutaria⁴, Shib Kumar Nath⁵, Drishti Bhatt⁶, Santosh Kumar⁷ & Prachi Desai⁸

Affiliation

¹Department of Prosthodontics, Bhabha College of Dental Sciences, Bhopal, M.P., India; ²Midtown Dental Group, New Jersey, USA; ³Department of Oral and Maxillofacial Surgery, Rungta College of Dental Sciences and Research, Kohka Kurud, Bhilai, Chhattisgarh, India; ⁴Department of Oral Medicine and Radiology, Gujarat University, Gujarat, India; ⁵Department of Orthodontics, The Smile Architect Dental Clinic and Braces Centre, Agartala, Tripura, India; ⁶Department of Oral and Maxillofacial Surgery, Divya Jyoti College of Dental Sciences and Research, Modinagar, Uttar Pradesh, India; ⁷Department of Periodontology, Karnavati School of Dentistry, Karnavati University, Gandhinagar, Gujarat, India; ⁸Oral Pathology and Microbiology, Ahmedabad Dental College and Hospital, Ahmedabad, India;

Email

Shilpi Khare - E-mail: drshilpi.iiphg@gmail.com

Hitika P Doda- E-mail:hitikadoda189@gmail.com; Phone: +1 206244337

Vanya Dubey- E-mail:vanyadubey555@gmail.com; Phone: +91 9111131116

Shreyansh Sutaria - E-mail:shreyanshutaria108@gmail.com; Phone: +91 9601163889

Shib Kumar Nath - E-mail:shibkumarnath@gmail.com; Phone: +91 8358003063

Drishti Bhatt - E-mail:db16791@gmail.com; Phone: +91 9738113216

Santosh Kumar - E-mail:drsantoshkumar2004@gmail.com; Phone: +91 7802800375

Prachi Desai - E-mail:Drprachishah.1@gmail.com; Phone: +91 9978229082

Article Type

Research Article

Date

Received December 1, 2023; Revised December 31, 2023; Accepted December 31, 2023, Published December 31, 2023

It is of interest to compare 0.2% chlorhexidine gel, 0.2% chlorhexidine chip, minocycline microspheres and slow-release doxycycline gel and tetracycline fibers as drug delivery systems in the management of peri-implantitis. The study comprised of 105 Indian participants who had a minimum of one dental implant with a probing depth of 4 mm, along with exudate and/or bleeding upon probing along with the presence of potentially harmful germs. The use of minocycline microspheres and 0.2% chlorhexidine gel resulted in significant improvements in probing depths at 1 month, 3 months and 6 months and all treatments showed decline in the indicator bacteria. Thus, minocycline microspheres and 0.2% chlorhexidine gel is useful as an adjuvant for mechanical debridement in management of peri-implantitis.

Keywords

Local drug delivery, chlorhexidine, peri-implantitis

Citation

Khare et al. Bioinformation 19(13): 1301-1306 (2023)

Edited by

Vini Mehta & Hiroj Bagde

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.