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Antimicrobial and anti-inflammatory activity of Terminalia arjuna



R. Vijayalakshmi*,1, N. Ambalavanan1, S. Rajeshkumar2 & Jaideep Mahendra1



1Department of Periodontology, Meenakshi Ammal Dental College & Hospital, Maduravoyal, Chennai, India; 2Nanobiomedicine Lab, Saveetha dental college & Hospital, SIMATS, Saveetha University, Chennai, India; *Corresponding author



R. Vijayalakshmi - E-mail: drvijaya.perio@madch.edu.in; Phone: +91 9444765440

N. Ambalavanan E-mail: profhod.perio@madch.edu.in

S. Rajeshkumar E-mail: rajeshkumars.sdc@saveetha.com

Jaideep Mahendra E-mail: drjaideep.perio@madch.edu.in


Article Type

Research Article



Received February 1, 2023; Revised February 28, 2023; Accepted February 28, 2023, Published February 28, 2023



Terminalia arjuna is one of the important herbal plants with cardioprotective, antihyperlipidemic activity and many more applications. In the present investigation, In order to find out the protective role, we prepared aqueous and ethanolic extract of Terminalia arjuna. The objective of this study was to comparatively evaluate the antimicrobial and anti-inflammatory activity of aqueous and ethanolic extract of Terminalia arjuna and to compare between the two. Antimicrobial activity of the plant extract was assessed by using agar well diffusion method against oral pathogens. The anti-inflammatory activity of prepared Terminalia arjuna plant extract was analyzed using egg albumin denaturation assay. The results of this study, showed that both aqueous and ethanolic extract had very good antimicrobial activity against Staphylococcus aureus, Pseudomonas species followed by Escherichia coli. However, the aqueous extract showed higher anti-inflammatory activity when compared with ethanolic extract. So it can be concluded that aqueous extract of Terminalia arjuna could be used as a local drug delivery agent in the treatment of chronic periodontitis.



Terminalia arjuna, local drug delivery, chronic periodontitis, antimicrobial, anti-inflammatory



Vijayalakshmi et al. Bioinformation 19(2): 184-189 (2023)


Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.