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Anti-inflammatory and antioxidant property of a novel floral mouthwash



Iram Rafique Pawane & Arvina Rajasekar*



Department of Periodontics, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai - 600077, India; *Corresponding author



Iram Rafique Pawane - Email: 152005004.sdc@saveetha.com;
Arvina Rajasekar - Email: arvinar.sdc@saveetha.com;


Article Type

Research Article



Received April 1, 2023; Revised April 30, 2023; Accepted April 30, 2023, Published April 30, 2023



It is of interest to prepare and evaluate the antioxidant and anti-inflammatory activity of a novel Clitoria ternatea and Matricaria chamomilla infused mouthwash. The floral extract using the two flowers in dried form was prepared in concentrations of 10μL, 20μL, 30μL, 40μL and 50μL. To assess the antioxidant activity, DPPH assay was done with L-ascorbic acid as the control agent. The anti-inflammatory activity of the floral extract was assessed by the Albumin Denaturation Assay for which diclofenac sodium was used. The absorbance value of the floral extract was determined for each of the concentrations for the antioxidant and anti-inflammatory properties. After 50 μL the prepared extract began to show close absorbance values compared to the standard solutions; at this concentration, the mouthwash was prepared. The preparation and evaluation of the floral extract of Clitoria ternatea and Matricaria chamomilla infused mouthwash shows promising anti-inflammatory and antioxidant properties and can be used as an adjunct in oral hygiene practices to reduce gingival inflammation. Further clinical studies using the prepared mouthwash are needed to test its efficacy.



Antioxidant, anti-inflammatory, inflammation, mouthwash, oxidative stress



Pawane & Rajasekar, Bioinformation 19(4): 407-410 (2023)


Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.