HOME   |    PDF   |   


Prevalence of TTI among Indian blood donors



Sanjay Kumar Thakur1, 2, Sompal Singh2, Dinesh Kumar Negi2 & Anil Kumar Sinha1*



1P.G. Department of Zoology, Veer Kunwar Singh University, Ara, Bihar, India - 802301; 2Department of Regional Blood Transfusion Centre, Hindu Rao Hospital and NDMC Medical College, Delhi, India 110007; *Corresponding author



Sanjay Kumar Thakur- E-mail: sanjaykumarthakur80@gmail.com, ORCID ID: https://orcid.org/0000-0001-8358-2517

Sompal Singh- E-mail: sompal151074@gmail.com, ORCID ID:http://orcid.org/0000-0002-7766-4708

Dinesh Kumar Negi- E-mail: dineshnegi2008@gmail.com, ORCID ID: https://orcid.org/0000-0002-5197-9082

Anil Kumar Sinha- E-mail: anilksinha2010@gmail.com, ORCID ID: https://orcid.org/0000-0002-9866-220X


Article Type

Research Article



Received May 1, 2023; Revised May 31, 2023; Accepted May 31, 2023, Published May 31, 2023



Transfusion Transmissible Infections (TTIs) such as human immune-deficiency virus (HIV-I/II), hepatitis B virus (HBV), Hepatitis C virus (HCV), Malaria parasite (MP) and syphilis can spread through contaminated blood or blood products. The present study was designed to analyze the prevalence of TTIs and their association with blood group, among the blood donors of Delhi. Blood group was determined by hem-agglutination using Gel card. HIV, HBV, and HCV test was performed by ELISA, syphilis by RPR and MP rapid card method. A total of 345(2.038%) blood donors were positive for TTIs. Prevalence of HBV, HCV, HIV-I/II, syphilis and MP were 188(1.111%), 73(0.431%), 34(0.201%), 49(0.29%) and 1(0.006%) respectively. Our result shows a trend of decrease in prevalence of TTIs; 2.267%, 2.111% and 1.614% between the year 2020, 2021 and 2022 respectively. Significant association of syphilis infection (P=0.036) and HCV infection (P=0.012) with ABO blood group antigen was observed. Blood group O donors were 1.81 times more infected with syphilis compared to donor having A and B antigen. Donors having blood group antigen B were 1.80 times more infected with HCV compared to donor not having B antigen. HBV and HIV prevalence found to be not associated with ABO and Rh blood group antigens. A low prevalence of TTIs positivity was observed among blood donors. Public awareness, proper counseling, medical examination and testing can help to minimize TTIs.  Our study results shows ABO blood group has an association with HCV and VDRL infection. 



Blood Donors, Transfusion Transmissible Infections, Blood group.



Thakur et al. Bioinformation 19(5): 582-589 (2023)


Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.