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Antibacterial, antioxidant and anti-inflammatory activity zinc-titanium dioxide nanocomposite



Mary Sheloni Missier*, Mahesh Ramakrishnan, Saravana Dinesh Sudalaimani Paulpandian, Shanmugam Rajeshkumar & Milling Tania



Department of Orthodontics, Saveetha Dental College and Hospital, SIMATS, Saveetha University, Chennai, Tamilnadu, India; *Corresponding author



Mary Sheloni Missier - E-mail: shelonibds@gmail.com

Mahesh Ramakrishnan - E-mail: mahesh@saveetha.com

Saravana Dinesh Sudalaimani Paulpandian - E-mail: drsaravanadinesh@gmail.com

Shanmugam Rajeshkumar - E-mail: rajeshkumars.sdc@saveetha.com

Milling Tania - E-mail: drtania_d@yahoo.co.in


Article Type

Research Article



Received May 1, 2023; Revised May 31, 2023; Accepted May 31, 2023, Published May 31, 2023



The current study concentrated on the green synthesis of Zinc-titanium dioxide nano-composite (Zn-TiO2 NC) through the use of lemon extract, optimizing the different experimental factors required for the formation and stability of nanocomposite. The preparation of nanocomposite was confirmed by the observation of the colour change and the surface plasmon resonance band was found at 380 nm, utilizing UV-Visible analysis. The TEM analysis, the morphological features of the prepared nanocomposite was identified to be spherical shape with mean particle size of 25 nm. In addition, the antibacterial, antioxidant, and anti-inflammatory activity of this nano-composite were also investigated. The biosynthesized nanocomposite showed excellent antibacterial activity against S. mitis and S. mutans. The obtained results indicate that the antioxidant and anti-inflammatory activity of this nanocomposite is significant. This bioactive nanocomposite can be used as an effective antibacterial, antioxidant and anti-inflammatory agent in biomedical and pharmacological fields for future applications.



Zinc-Titanium nano-composite, lemon extract, antibacterial, antioxidant, anti-inflammatory agent



Missier et al. Bioinformation 19(5): 638-643 (2023)


Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.