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Clinical and bacteriological profile of community acquired pneumonia in hospitalized children



Damodharan Perumal1, Heamchandsaravanan Anandha Krishnan Rajaram1, Karthick Shanmugam1, Judith Gracia2, Bowiya Ponnusamy1, Madhan Krishnan3& Prabu Dhandapani1*



1Department of Microbiology, Dr. ALM PG Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai- 600113, Tamilnadu, India; 2Center for Advanced studies in Crystallography and Biophysics, University of Madras, Guindy Campus, Chennai - 600085, Tamilnadu, India; 3Research, Chettinad Hospital and Research Institute, Chettinad Academy of Research and Education, Kelambakkam-603103, Tamilnadu, India; *Corresponding author



DamodharanPerumal- E-mail: 17damzz@gmail.com

Heamchandsaravanan Anandha Krishnan Rajaram - E-mail: heamchand0314@gmail.com

Karthick Shnamugam-E-mail: karthickishore16@gmail.com

Judith Gracia-E-mail: judith.graciaj@gmail.com

Bowiya Ponnusamy-E-mail:bowikeerthi1998@gmail.com

Madhan Krishnan-E-mail:kmadhan91@gmail.com; drmadhan@care.edu.in

*Prabu Dhandapani-E-mail:bruibms@gmail.com


Article Type

Research Article


Received June 1, 2023; Revised June 30, 2023; Accepted June 30, 2023, Published June 30, 2023



Community-acquired pneumonia (CAP) is the leading cause of mortality and morbidity with important clinical impact across the World. India accounts for 23 per cent of global pneumonia burden with case fatality rates between 14 and 30 per cent. Pneumonia is basically classified into typical and atypical pneumonia. Emerging evidence indicates that dual typical and atypical bacterial infections function synergistically in many cases and together likely enhance the severity of CAP. However, the optimal management of CAP in children is still not well defined and the diagnosis is challenging when based solely on clinical observations since the common symptoms of CAP, especially at an early stage, are similar to those of ordinary respiratory tract infections. So RT-PCR is a rapid and precise molecular technique is used for rapid detection of bacteria causing community acquired pneumonia. A total of 268 samples were tested for the respective bacterial pathogens, among the tested the most common pathogen was Haemophilus influenzae (18.3%, 49/268) followed by S. pneumoniae (14.6%,39/268), M. catarhallis (9.3%,25/268),M. pneumoniae (9%, 24/268), B. parapertusis (3.4%,9/268), B. pertusis (1.5%, 4/268), C. pneumoniae (1.5%, 4/268), C. burnetti (1.1%, 3/268)and L. pneumophila (0.74%, 2/268). H. influenza and S. pneumoniae were the most commonly detected organisms among the community acquired pneumonia patients.



Community-acquired pneumonia; typical pathogens; atypical pathogens; Pneumonia; RT-PCR.



Perumal et al. Bioinformation 19(6): 781-785 (2023)


Edited by

P Kangueane






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.