Title

Antioxidant, antibacterial and antiviral effect of the combination of ginger and garlic extracts

Authors

Saravanan Rajendrasozhan^*

Affiliation

Department of Chemistry, College of Sciences, University of Ha'il, Ha'il 55473, Saudi Arabia

Email

Saravanan Rajendrasozhan - Email; s.rajendrasozhan@uoh.edu.sa

Article Type

Research Article

Date

Received January 1, 2024; Revised January 31, 2024; Accepted January 31, 2024, Published January 31, 2024

Garlic and ginger are well known as safe alternatives to traditional therapies. Limited information exists regarding antioxidant, antibacterial and antiviral capabilities of the combination of ginger and garlic. Standard methodologies were employed to determine the phytochemical compositions. Antioxidant activities were evaluated through DPPH and FRAP assays. Notably, in DPPH assay, combination of ginger and garlic extracts displayed significantly higher (85.44%, p < 0.005) antioxidant activity even at lower concentrations (6 mg/ml) compared to ginger and garlic extracts alone. Similar findings were observed for FRAP assay. At low concentration of extracts (25 μg/ml), combination of ginger and garlic exhibited significant (p < 0.005) increase in reducing activity (51%) compared to ginger or garlic extracts alone. Significant antibacterial and antiviral activities were exhibited by the combination of both ginger and garlic extracts as compared to ginger and garlic extracts alone. The combined effect of garlic and ginger exhibited a synergistic effect in bacterial and viral growth inhibition. These findings suggest that the diverse phytochemical compositions of the ginger and garlic varieties contribute to their strong antioxidant properties, potentially positioning them as valuable therapeutics for bacterial and viral infections. Further analysis will be required for their widespread utilization and pharmaceutical applications.

Keywords

Citation

Rajendrasozhan, Bioinformation 20(1): 11-17 (2024)

Edited by

P Kangueane

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.