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Title

Serum Mg, Zn and Fe levels among coronary artery disease patients in an urban south Indian region

 

Authors

G Lakshmi Swetha1, Reshma Devarajachar2, Harish Rangareddy3,*, Chethana Chethan4 & H. Srinivas5

 

Affiliation

1Department of Community Medicine, Sapthagiri Institution of Medical Sciences, Bangalore, India; 2Department of Biochemistry, BGS Global Institute of Medical Sciences, Bangalore, India; 3Department of Biochemistry, Haveri Institute of Medical Sciences, Haveri, India; 4Department of Biochemistry, BGS Global Institute of Medical Sciences, Bangalore, India; 5Department of Biochemistry, BGS Global Institute of Medical Sciences, Bangalore, India

 

Email

G Lakshmi Swetha - Email: gl.swetha1996@gmail.com; Phone number: +91-8333813789

Reshma Devarajachar - Email: dr.reshma17@gmail.com; Phone number: +91-8792594024

Harish Rangareddy - Email: harishreddy1349@gmail.com & bgsgimsbiochem@gmail.com;

Phone number: +91-9845355050

Chetana Chetan - Email: chetanackumar@yahoo.com; Phone number: +91-9986739124

Srinivas H - Email: drsrinibiochem@gmail.com; Phone number: +91-9310023633

 

Article Type

Research Article

 

Date

Received January 1, 2024; Revised January 31, 2024; Accepted January 31, 2024, Published January 31, 2024

 

Abstract

Nutrition plays a crucial role in CAD development, with trace elements like zinc, magnesium, copper, and iron impacting atherogenesis through their antioxidant or oxidant activity. This cross sectional study was conducted under the ICMR-STS program with IEC approval with the aim to estimate and correlate serum magnesium, zinc, and iron levels in CAD patients compared to healthy Individuals in the Urban South Indian population (50 cases, 50 controls, aged 40-70 years). Statistical analyses revealed a significant difference in serum iron levels between cases (95.10 38.82 μg/dL) and controls (118.30 50.54 μg/dL) with a p-value of 0.012. Serum magnesium levels showed a marginal difference between cases (1.970.11 mg/dL) and controls (1.920.15 mg/dL) with a p-value of 0.053. However, serum zinc levels did not exhibit a statistically significant difference between cases (123.47 26.35 mg/dL) and controls (118.90 32.77 mg/dL) with a p-value of 0.445. Thus, data shows the association between low serum iron levels and an increased risk of coronary artery disease.

 

Keywords

trace elements, oxidative stress, coronary artery disease

 

Citation

Swetha et al. Bioinformation 20(1): 70-73 (2024)

 

Edited by

P Kangueane

 

ISSN

0973-2063

 

Publisher

Biomedical Informatics

 

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.