Title

Evaluation N-Telopeptide (NTx) and calprotectin level in crevicular fluid with peri-implantitis

Authors

Ashwini Narayankar¹, Sagar Kumar Kashyap², Suman Yadav³, Anas Abdul Khader⁴, Anjaneya Dube⁵, Pushkar Gupta⁶, Nureldeen AN Elhammali⁷ & Abhaya Chandra Das^8,*

Affiliation

¹Department of Prosthodontics, SB Patil Dental College, Bidar, Karnataka, India; ²Intern, Kalinga Institute of Dental Sciences, Bhubaneswar, Odisha, India; ³Department of Oral Surgery, ITS Dental College, Modinagar, UP, India; ⁴Department of Periodontology and Implant Dentistry, College of Dentistry, Qassim University, Kingdom of Saudi Arabia; ⁵Department of Oral and Maxillofacial Surgery, Hitkarini Dental College and Hospital, Jabalpur, MP, India; ⁶Department of Prosthodontics and Crown & Bridge, Hitkarini Dental College and Hospital, Jabalpur, MP, India; ⁷Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Sirte University, Libya; ⁸Department of Periodontics and Oral Implantology, Institute of Dental Sciences, Siksha 'O' Anusandhan (Deemed to be University), Khandagiri Square, Bhubaneswar - 751030, Odisha, India; *Corresponding author

Email

Ashwini Narayankar - E - mail: ash_17_wins@yahoo.co.in; Phone: +91 9604618260
Sagar Kumar Kashyap - E - mail: kashyapsagark@gmail.com; Phone: +91 6003650855
Suman Yadav - E - mail: drsumanomfs@gmail.com; Phone: +91 9891410322
Anas Abdul Khader - E - mail: an.muhammed@qu.sa; Phone: +91 808774727
Anjaneya Dube - E - mail: drdube@gmail.com; Phone: +91 9631576656
Pushkar Gupta - E - mail: drpushkar1@gmail.com; Phone: +91 9406538208
Nureldeen AN Elhammali - E - mail: nurdentnur@yahoo.com; Phone: +00218911361480
Abhaya Chandra Das - E - mail: drabhaya2011@gmail.com; Phone: +91 7008093223

Article Type

Research Article

Date

Received September 1, 2024; Revised September 30, 2024; Accepted September 30, 2024, Published September 30, 2024

Abstract

Following inflammation and bone loss near the implant site, peri-implantitis develops. N-Telopeptide (NTx) and Calprotectin are abundant in the crevicular fluids found in that area, and are thought to be possible biomarkers. Therefore, it is of interest to evaluate the amounts of calprotectin and NTx in the peri-implant sulcular fluid (PISF) from implant sites with or without peri-implantitis. Twenty healthy individuals and twenty patients with peri-implantitis who had a single dental implant were included in the total of forty participants. For every patient, the peri-implant clinical parameters of gingival index (GI), probing depth (PD), and bleeding on probing (BOP) were ted. To evaluate the bone loss (BL), radiographic pictures of every implant were acquired. Using sterile paper strips, PISF was gathered in order to use the ELISA technique to measure the amounts of NTx and calprotectin. We examined the correlations between the levels of PISF, NTx, and calprotectin with the peri-implant clinical indicators. In comparison to the healthy group, the peri-implantitis group had increased levels of NTx and calprotectin. In individuals with peri-implantitis, the levels of NTx and calprotectin in the PISF may be a promising indicator for bone loss and peri-implant inflammation.

Keywords

Biomarkers, calprotectin & peri-implantitis

Citation

Narayankar et al. Bioinformation 20(9): 1183-1186 (2024)

Edited by

P Babaji

ISSN

0973-2063

Publisher

Biomedical Informatics

License

This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.