Title
Longitudinal assessment of cardio-respiratory fitness among Indian patients with type 2 diabetes mellitus
Authors
Sushmita Palia1, Mounish Reddy2, Shreya Seira Honarius3, Madhurika Jalakam4, Ruchi Kothari5,*, Mayur Wanjari6, Labdhi Sangoi7 & Ravi Sangoi8
Affiliation
1Department of Cardiology, All India Institute of Medical Science, Guntur District, Mangala Giri, Andhra Pradesh 522503, India; 2Department of Emergency Medicine, Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom; 3Resident Doctor (Cardiology) St. Johns Medical College, Bangalore, India; 4SHO, ITU Department, Queen Elizabeth The Queen Mother Hospital, Kent CT9 4AN East Kent Hospitals University NHS Foundation Trust, St Peters Road, Margate, England; 5Department of Physiology, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, India; 6Department of Research, Datta Meghe Institute of Higher Education & Research (DMIHER), Sawangi, Maharashtra, India; 7Department of Research, Government Medical College, Jalna, Maharashtra; 8Department of Internal Medicine, Government Medical College, Baramati, India; *Corresponding author
Sushmita Palia - E - mail: sushmithapaila9@gmail.com; +918790921899
Mounish Reddy - E - mail: drmounishreddy@gmail.com; +917093939958
Shreya Seira Honarius - E - mail: drssh2312@gmail.com; +919742240605
Madhurika Jalakam - E - mail: jalakamm@gmail.com; +447477683913
Ruchi Kothari - E - mail: ruchi@mgims.ac.in; +919730216884
Mayur Wanjari - E - mail: Wanjari605@gmail.com; +918007356104
Labdhi Sangoi - E - mail: labdhisangoi101@gmail.com; +917259404071
Ravi Sangoi - E - mail: ravisangoi35@gmail.com; +9190220589548
Article Type
Research Article
Date
Received October 1, 2024; Revised October 31, 2024; Accepted October 31, 2024, Published October 31, 2024
Abstract
Type 2 Diabetes Mellitus (T2DM) is associated with many complications, including cardiovascular and autonomic dysfunctions. Cardiorespiratory fitness as estimated by maximal oxygen uptake (VO2 max) is a very powerful predictor of cardiovascular health. Therefore, it is of interest to measure the cardiorespiratory parameters in T2DM patients for diagnosing autonomic dysfunction and to follow the changes over time. Baseline and follow-up cardiorespiratory fitness parameters among patients of Central India suffering from T2DM and its effectiveness to lifestyle modifications for these parameters are done. This hospital-based longitudinal study was conducted on 600 patients between the age group of 30 and 65 years diagnosed with T2DM. Patients were recruited from the Sports Physiology Laboratory, Department of Physiology, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Maharashtra. Baseline measurements of VO2 max, HRV and other cardiorespiratory variables were taken with a motorized treadmill using Lab Chart. Then, lifestyle counselling was undertaken for the participants, and the same parameters were reassessed one year later. Statistical package SPSS version 23 was used during data analysis. After one year of interventions, the improvements at the end of one year include those of VO2 max and HRV. The mean VO2 max improved from 25.4 ± 5.2 to 30.1 ± 4.8 ml/kg/min while the probability was less than 0.001. The main indices of HRV showed improved autonomic balance along with enhanced parasympathetic activity. Combining lifestyle interventions with regular monitoring of cardiorespiratory fitness and HRV can, indeed significantly improve cardiovascular health in T2DM patients. This study calls for the inclusion of fitness assessments in everyday clinical care for diabetes.
Keywords
Diabetes mellitus, cardiorespiratory, longitudinal study, autonomic dysfunction, sports physiology
Citation
Palia et al. Bioinformation 20(10): 1261-1265 (2024)
Edited by
Hiroj Bagde MDS, (PhD), PGDCR, PGDHHM, PGDL, PGDM
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
