Title
Visual evoked potentials among Indian patients with optic nerve disorders
Authors
Ruchi Kothari1,*, Sai Shanmukh Vemparala2, Siraj Muhammed Shafy3, Mayur Wanjari4, Labdhi Sangoi5 & Ravi Sangoi6
Affiliation
1Department of Physiology, Mahatma Gandhi Institute of Medical Sciences, Sevagram, Wardha, Maharashtra, India; 2Department of Physiology, Andhra Medical College, Medical College Road King George Hospital, opp. Collector Office, Maharani Peta, Visakhapatnam, Andhra Pradesh, India; 3Department of Medicine, Jawaharlal Nehru Medical College, Belgaum, KLE University Campus, Nehru Nagar, Belagavi, Karnataka, India; 4Department of Research, Datta Meghe Institute of Higher Education & Research (DMIHER), Sawangi, Maharashtra, India; 5Deprtment of Research, Government Medical College , Jalna, Maharashtra; 6Depertment of Internal Medicine, Government Medical College and General Hospital, Baramati, Pune, Maharashtra, India; *Corresponding author
Ruchi Kothari - E - mail: ruchi@mgims.ac.in; Phone: +91 9730216884
Sai Shanmukh Vemparala - E - mail: drshanmukh@hotmail.com; Phone: +91 9912980994
Siraj Muhammed Shafy - E - mail: sirajmshafy@gmail.com; Phone: +91 8762047066
Mayur Wanjari - E - mail: Wanjari605@gmail.com; Phone: +91 8007356104
Labdhi Sangoi - E - mail: labdhisangoi101@gmail.com; Phone: +91 7259404071
Ravi Sangoi - E - mail: ravisangoi35@gmail.com; Phone: +91 9022059548
Article Type
Research Article
Date
Received October 1, 2024; Revised October 31, 2024; Accepted October 31, 2024, Published October 31, 2024
Abstract
Optic nerve disorders comprise a large part of causes of visual impairments and can be associated with various clinical presentations. Accurate diagnosis and treatment sometimes would be achieved by using advanced techniques in diagnostic approaches such as Visual Evoked Potentials (VEP). This study therefore profiles optic nerve disorders and estimates the role VEP plays in the diagnosis and prognosis of these conditions in a rural tertiary care hospital. Hundred cases diagnosed with optic nerve disorders and 200 controls matched for age and gender were recruited from the Eye OPD. Structured questionnaires, clinical examination and VEP testing were done to retrieve information. Analysis by SPSS version 23 was carried out. In the study, the most common disorders found were optic neuritis, followed by ischemic optic neuropathy, and then glaucoma. VEP revealed statistical abnormalities concerning P100 latency and amplitude in the patients with optic nerve disorders as compared to controls. P100 latency was significantly prolonged with a mean comparison of p<0.001, while the amplitude was reduced with p<0.001 when compared to the controls. VEP is an important diagnostic and prognostic tool in optic nerve diseases. It would tend to provide objective and reproducible data, thus helpful for early detection and management.
Keywords
Optic nerve, visual evoked potentials, case control, visual impairments, diagnosis.
Citation
Kothari et al. Bioinformation 20(10): 1266-1270 (2024)
Edited by
Hiroj Bagde MDS, (PhD), PGDCR, PGDHHM, PGDL, PGDM
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
