Title
The ctDNA revolution: Insights on cancer care: A narrative review
Authors
Krutika Mahendra Gohil1,*, Jyothika Venkataswamy Reddy2, Saniya Kifayetulla Mulla1, Rutu Snehal Shah3, Shrunga Kandhi Raghavendra2, Rishika Singh1 & Sagar Mahendra Gohil4
Affiliation
1Department of Internal Medicine, Hinduhridaysamrat Balasaheb Thackarey Medical College (HBTMC) and Dr. Rustom Narsi Cooper Municipal General Hospital, Mumbai, Maharashtra, India; 2Department of Medicine, Chamarajanagar Institute of Medical Sciences, Chamarajanagar, Karnataka, India; 3Department of Medicine Dr. Vaishampayan Memorial Government Medical College, Solapur, Maharashtra, India; 4Department of Medicine Mahatma Gandhi Mission Institute of Health Sciences, Navi Mumbai, Maharashtra, India; *Corresponding author
Krutika Mahendra Gohil - E - mail: krutikagohil1998@gmail.com; Phone: +91 9769125762
Jyothika Venkataswamy Reddy - E - mail: jyothikavreddy3004@gmail.com; Phone: +91 7483665876
Saniya Kifayetulla Mulla - E - mail: saniyambbs11@gmail.com; Phone: +91 9167820705
Rutu Snehal Shah - E - mail: rutushah25998@gmail.com; Phone: +91 7738644048
Shrunga Kandhi Raghavendra - E - mail: shrungakr1999@gmail.com; Phone: +91 9535357441
Rishika Singh - E - mail: rishikasingh2000@gmail.com; Phone: +91 8451970433
Sagar Mahendra Gohil - E - mail: sagar.gohil1305@gmail.com; Phone: +91 9867105762
Article Type
Review
Date
Received October 1, 2024; Revised October 31, 2024; Accepted October 31, 2024, Published October 31, 2024
Abstract
Circulating tumor DNA (ctDNA) is a revolutionary tool in the detection and monitoring of cancer: a minimally invasive, highly sensitive approach to analysing tumor-specific DNA in the bloodstream. Therefore, it is of interest to explore the current and evolving landscape of cancer genomics as precision tools in quantifying tumor dynamics. Thus, the role of ctDNA in tracking minimum residual disease, relapse, recurrence and the tailoring of therapeutic strategies for effective management of tumours is reviewed.
Keywords
ctDNA, tumor specific DNA, cancer, predictive marker, genomics
Citation
Gohil et al. Bioinformation 20(10): 1287-1290 (2024)
Edited by
Hiroj Bagde MDS, (PhD), PGDCR, PGDHHM, PGDL, PGDM
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
