Title
The role of extra-corporeal radiation therapy for osteo-sarcoma
Authors
Krutika Mahendra Gohil1,*, Sidharth Misra2, Jyothika Venkataswamy Reddy3, Shrunga Kandhi Raghavendra3, Rishika Singh1, Bratish Poddar2 & Pooja Tawate4
Affiliation
1Department Medicine, Hinduridaysamrat Balasaheb Thackeray Medical College and Dr. Rustom Narsi Cooper Municipal General Hospital, Mumbai, Maharashtra, India; 2Department Medicine, Armed Forces Medical College, Pune, India; 3Department of Medicine, Chamarajanagar Institute of Medical Sciences, Chamarajanagar, Karnataka, India; 4Department of Medicine, Government Medical College and Hospital, Miraj, Maharashtra, India; *Corresponding author
Krutika Mahendra Gohil - E - mail: krutikagohil1998@gmail.com; Phone: +91 9769125762
Sidharth Misra - E - mail: misra.sidharth.afmc@gmail.com; Phone: +91 7875455007
Jyothika Venkataswamy Reddy - E - mail: jyothikareddy3004@gmail.com; Phone: +91 7483665876 Shrunga Kandhi Raghavendra - E - mail: shrungakr1999@gmail.com; Phone: +91 9535357441
Rishika Singh - E - mail: rishikasingh2000@gmail.com; Phone: +91 8451970433
Bratish Poddar - E - mail: bratish.poddar@gmail.com; Phone: +91 7408688004
Pooja Tawate - E - mail: poojatawate21@gmail.com; Phone: +91 7710856251
Article Type
Research Article
Date
Received October 1, 2024; Revised October 31, 2024; Accepted October 31, 2024, Published October 31, 2024
Abstract
Extracorporeal radiation therapy is a new limb-salvaging procedure increasingly used, especially in situations where it may not be possible to carry out complete surgical resection. Osteosarcoma is a malignant tumour of bone that, typically, presents in young people, and often, it is managed by using different modes of treatment, which include surgery and chemotherapy. This therapy involves the removal of the involved segment of bone, its extracorporeal irradiation, followed by re-implantation to preserve limb function and reduce the risk of recurrence. Therefore, it is of interest to review the effectiveness of, clinical uses, and results of ECRT, focusing on its benefits in terms of bony conservation and decreased complications with either prosthetics or allografts. Promising local control and survival rates further cement its potential.
Keywords
Extracorporeal radiation therapy, osteosarcoma, Ewing's sarcoma, Re-implantation
Citation
Gohil et al. Bioinformation 20(10): 1329-1335 (2024)
Edited by
Hiroj Bagde MDS, (PhD), PGDCR, PGDHHM, PGDL, PGDM
ISSN
0973-2063
Publisher
License
This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
