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Evaluation of CoVid-19 infection among vaccinated and unvaccinated individuals using biochemical markers



Allavarapu Ramya Sree1,*, K. Sethumadhavan1, S.P. Tejaswi Pullakanam 2 & Purimitla Usharani3



1Department of Microbiology, Aarupadai Veedu Medical College and Hospital, Vinayaka Mission's Research Foundation (VMRF-DU), Puducherry, Tamil Nadu, India; 2Department of Biochemistry, Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Marikavalasa, Visakhapatnam, Andhra Pradesh, India; 3Department of Microbiology, Dr. Patnam Mahender Reddy Institute of Medical Sciences, Chevella, Ranga Reddy District, Telangana, India; *Corresponding author



Allavarapu Ramya Sree - E-mail: ramyams619@@gmail.com; Phone: +91 9491726905

K Sethumadhavan - E-mail: sethumadhavanmicro@gmail.com; Phone: 0413-2611246

S.P. Tejaswi Pullakanam - E-mail: tejaswibio22@gmail.com; Phone: +91 8985081842

Purimitla Usharani - E-mail: purimitlausha2@gmail.com; Phone: +91 6304297389


Article Type

Research Article



Received March 1, 2024; Revised March 31, 2024; Accepted March 31, 2024, Published March 31, 2024



The evaluation of infection rate for CoVid-19 cases among vaccinated and unvaccinated individuals using haematological parameters is of interest. Data such as age, gender, occupation, location, signs and symptoms, length of symptoms, date of sample collection and report generation, status of vaccinations, and outcome available in the database was used in this analysis. Ferritin levels, D-dimer values, CRP, troponin-1 levels and platelet count of each CoVid-19 patient were recorded and analysed. Data shows that maximum number of cases was reported during the second wave 143 (51.07%). The common age group affected was 31-40 years 28.56%. The common symptom identified was weakness in arms and legs among the unvaccinated group of CoVid-19 positive group. However, common symptom identified was fatigue (87%) among those who received only the first dose of CoVid vaccine. Nonetheless, the symptom identified was hair loss (68%) among those who received both the doses of CoVid vaccine. Thus, data shows that people do experience severe and life-threatening COVID-19 infection despite receiving the vaccination. Nonetheless, the infection is mild and very few individuals require hospitalization. No deaths are reported in the group that received the vaccination. This is in contrast to the unvaccinated group, which had a severe CoVid-19 infection with few deaths reported.



CoVid-19, vaccinated, unvaccinated, symptoms, prevalence, ferritin, D-dimer, CRP



Ramya Sree et al. Bioinformation 20(3): 223-228 (2024)


Edited by

Peter N Pushparaj






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.