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Hematological profile of OSMF patients with increasing severity



Vinod Sargaiyan1,*, Simarjeev Singh2, Ruchira Shukla3, Abhishek Singh Tanwar4, Tarang Mehta5, Pranav V Manek6, Bhumika J Patel7 & Keyur Jitendrakumar Patel8,*



1Department of Oral Pathology and Microbiology, Maharana Pratap College of Dentistry and Research Center, Gwalior, M.P. India; 2Department of Oral Medicine and Radiology, Gian Sagar Dental College and Hospital, Patiala, Punjab, India; 3MDS, Private Consultant, Ortho expert Multispeciality Dental Clinic, Ambikapur, Chhattisgarh, India; 4Department of Oral and Maxillofacial Surgery, Geetanjali Dental and Research Institute, Udaipur, Rajasthan, India; 5Department of Oral and Maxillofacial Pathology and Oral Microbiology, Narsinbhai Patel Dental College and Hospital, Sankalchand Patel University, Gujarat, India; 6Department of Oral Medicine and Radiology, Pacific Dental College and Research Centre, Udaipur, Rajasthan, India; 7Department of Dentistry, Howard University, College of Dentistry, Washington DC, USA; 8Government Medical College, Surat, India; *Corresponding author



Vinod Sargaiyan - E-mail: dr.vinodsargaiyan@yahoo.co.in

Simarjeev Singh - E-mail: ddr.simar@gmail.com

Ruchira Shukla - E-mail: dr.ruchirashukla44@gmail.com

Abhishek Singh Tanwar - E-mail: abhigreatest@yahoo.com

Tarang Mehta - E-mail: tarangmehta111@gmail.com

Pranav V Manek - E-mail: dr_pranav15@yahoo.co.in

Bhumika J Patel - E-mail: bhumikapatel2687@gmail.com

Keyur Jitendrakumar Patel - E-mail: drkeyurpatel22sep@gmail.com


Article Type

Research Article



Received April 1, 2024; Revised April 30, 2024; Accepted April 30, 2024, Published April 30, 2024



Haematological profile of patients with oral sub mucous fibrosis (OSMF) and its correlation with the severity of OSMF is evaluated. The study comprised of sixty participants with clinical diagnoses. They were divided into smaller groups based on the OSMF stage. Sixty age and gender matched healthy controls were chosen among patients presenting for routine hematological examinations and free of systemic illnesses. Assessment of iron, hemoglobin, and red cell indices in all study participants was carried out. It was observed that the values of haematological tests like (Hb (g/dL), PCV, MCV (fl), MCH, MCHC, Iron (mg/dL) and Vitamin B12 (pg/Ml) was greater in normal subjects as compared to OSMF patients. Values were found to decrease further as the severity (staging) of OSMF increased among OSMF patients. The findings were statistically significant showing decrease in the values of different haematological parameters as the stage of OSMF progressed from stage I to stage III.



Haematological profile, OSMF, severity



Sargaiyan et al. Bioinformation 20(4): 353-357 (2024)


Edited by

Vini Mehta






Biomedical Informatics



This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.